Single-player is relatively straightforward: you can play against up to five computer-controller opponents and get to murder solving.
The options with which to play might be restrictive and suboptimal, but the presentation and execution of this video game version of Clue is great. For better or worse, Clue on Switch is limited to single-player and online multiplayer modes, but those modes are incredibly well put together. When I heard that the classic board game was making its way to the platform, my mind raced with how it could be adapted for a local multiplayer experience, calling to mind fond memories of long lost Wii classic Guilty Party. I might have gotten a little ahead of myself with Clue on Nintendo Switch.
